Two sample MR report
DOCK9_Monocyte (Mono) against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | -0.1140381 | 0.1181661 | 0.5113163 |
| Weighted median | 3 | -0.0814373 | 0.0288794 | 0.0048037 |
| Inverse variance weighted | 3 | -0.0830030 | 0.0232060 | 0.0003478 |
| Simple mode | 3 | -0.0805554 | 0.0329641 | 0.1344850 |
| Weighted mode | 3 | -0.0797033 | 0.0338942 | 0.1430371 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.1218817 | 1 | 0.7270025 |
| Inverse variance weighted | 0.1936281 | 2 | 0.9077248 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0316316 | 0.1180921 | 0.8333892 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 3.02e-05 | 0 | TRUE | 0.6075336 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
